Biomedical Evidence Retrieval with Agentic RAG and Dual Text Encoders
Dhruv Goyal ⋅ Ema Seibert ⋅ Ryan Ding ⋅ Matteo Migliarini ⋅ Kevin Zhu
Abstract
We propose an agentic RAG framework for biomedical evidence retrieval that uses iterative query refinement across PubMed and MIMIC-IV clinical notes. Using dual domain-specific encoders and self-critique loops, our system achieves competitive results on PMC-Patients and PubMedQA benchmarks, demonstrating the value of adaptive retrieval for clinical decision support.
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