Materials informatics (MI) is a rapidly growing field, utilizing materials and chemicals R&D data to produce novel materials faster. The progress towards the goals of using MI at a large scale is hampered by the current reality of materials R&D data landscapes. In this paper, we will break down the unique challenges presented in preparing and storing materials and chemicals research data for MI, and will discuss a potential solution for enabling systematic enterprise-wide materials data storage and retrieval capable of unlocking MI across an organization.