Despite malaria’s tremendous impact on public health and economic development in Africa, and a 3 billion USD annual investment in its control, the prospect of a malaria-free Africa seems distant. In this session, I will discuss how Zzapp is harnessing AI and mobile technologies to address the key challenges to malaria elimination today. Through the use of deep learning algorithms, we are developing a planning tool that will design ever-improving intervention strategies, customized to individual urban and rural communities. To simplify the implementation of these strategies, and to ensure effective execution, we have launched a mobile app that relays instructions directly to workers in the field, and monitors them using GPS. In collaboration with several research institutes and malaria control programs in Africa, we adapt these tools to the current and future needs of malaria elimination campaigns.