A Principled Self-Referenced Early Stopping Approach for Deep Image Prior

Recently, Deep Image Prior (DIP) has demonstrated strong capabilities for solving inverse imaging problems (IIPs) by optimizing a randomly initialized convolutional neural network in a training-data-free regime. However, DIP suffers from overfitting to noisy measurements due to network over-parameterization, making early stopping (ES) essential. The most successful ES method tracks fluctuations in the running variance of the network output to detect overfitting. However, in many applications, these fluctuations may appear prematurely, leading to unstable reconstructions. In this paper, we first show that nearly optimal DIP early stopping can be achieved when two independent noisy copies of the degraded image are available. Motivated by this observation, and since obtaining two fully independent copies is infeasible, we propose an overfitting detection framework based on constructing pseudo self-referenced images, resulting in three IIP-specific algorithms. Our approach is further supported by theoretical results on single-reference validation, pseudo-validation estimation, and the impact of shared noise. Across different IIPs, ranging from natural image restoration to medical image reconstruction, and under varying noise levels and noise types, our methods consistently outperform existing DIP early stopping approaches, all without requiring knowledge of the measurement noise characteristics.