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Poster
in
Workshop: Medical Imaging meets NeurIPS

Ultra-Resolution Cascaded Diffusion Model for Gigapixel Image Synthesis in Histopathology

Sarah Cechnicka · Hadrien Reynaud · James Ball · Naomi Simmonds · Catherine Horsfield · Andrew Smith · Candice Roufosse · Bernhard Kainz


Abstract:

Diagnoses from histopathology images rely on information from both high and low resolutions of WSIs. URCDMs allow for the synthesis of high-resolution images that are realistic at all magnifications, focusing not only on fidelity but also on long-distance spatial coherency. Our model beats existing methods, improving the pFID-50k score by 110.63 to 39.52 pFID-50k. Additionally, a human expert evaluation study was performed, reaching a weighted Mean Absolute Error (MAE) of 0.11 for the LRDM and a weighted MAE of 0.22 for the URCDM.

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