Abstract: This workshop is designed to bring together trainees and experts in machine learning with those in the very forefront of biological research today for this purpose. Our full-day workshop will advance the joint project of the CS and biology communities with the goal of "Learning Meaningful Representations of Life" (LMRL), emphasizing interpretable representation learning of structure and principle. As last year, the workshop will be oriented around four layers of biological abstraction: molecule, cell, synthetic biology, and phenotypes.

Mapping structural molecular detail to organismal phenotype and function; predicting emergent effects of human genetic variation; and designing novel interventions including prevention, diagnostics, therapeutics, and the development of new synthetic biotechnologies for causal investigations are just some of the challenges that hinge on appropriate formal structures to make them accessible to the broadest possible community of computer scientists, statisticians, and their tools.